Brain and Behavior Animal Lab 4

Meeting location: SCA 007 (animal care facility) - bring lab coat!

Activities

1. Investigate the behavioral effects of hippocampal lesions.

2. Test the effect of expectations of reward on pain sensation threshold     

Students with divide into two teams. Each team will be given one lesioned and one sham lesioned rat (I will not tell you which is which). Each rat will be tested on the elevated plus maze (5 minutes) and the inhibitory avoidance box. For the plus maze, time how long the rat spends in the open and the closed arms. For the avoidance box, put the rat in the striped side and time how long it takes him to cross (use a 5-min time limit). 

What do you expect to see?  What did you see?  What if anything can we conclude?  We will discuss these and other issues.              

Students with divide into two teams. Each team will test 4 "hotplate" mice and 4 control mice (alternate between them). Verify that the hotplate is at 50 degrees Celsius. Record how long each mouse stayed on the hotplate before showing a pain response.

 

What do you expect to see?  What did you see?  What if anything can we conclude?  We will discuss these and other issues.              

            Procedural Note

Team 1 will test their mice first, and then their rats.

Team 2 will test their rats first, and then their mice.

After testing is complete, we will reconvene in GC008 to analyze and discuss the results.