Meeting location: SCA 007 (animal care facility) at 3:00 - bring your lab coat!

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Social behavior in mice fed an unhealthy vs. a healthy diet

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Procedure for the Social Response Test
 

This is a well-established paradigm to assess normal vs social deficits in mice. The test mouse is placed in the middle of a 3-compartment box made of plexiglass. Separating each compartment is a plexiglass “wall” with an opening in the center. Another mouse is placed within a see-through cage in the left compartment. An identical but empty cage in placed in the right compartment. The time the test mouse spends in the right and left compartments is recorded. Normal mice will spend more time in the compartment with the other mouse compared to the compartment with the empty cage.